d-limonene exhibits antitumor activity by inducing autophagy and apoptosis in lung cancer.
Identifieur interne : 000C04 ( Main/Exploration ); précédent : 000C03; suivant : 000C05d-limonene exhibits antitumor activity by inducing autophagy and apoptosis in lung cancer.
Auteurs : Xiao Yu [République populaire de Chine] ; Hongyan Lin [République populaire de Chine] ; Yu Wang [République populaire de Chine] ; Wenwen Lv [République populaire de Chine] ; Shuo Zhang [République populaire de Chine] ; Ying Qian [République populaire de Chine] ; Xiaobei Deng [République populaire de Chine] ; Nannan Feng [République populaire de Chine] ; Herbert Yu [États-Unis] ; Biyun Qian [République populaire de Chine]Source :
- OncoTargets and therapy [ 1178-6930 ] ; 2018.
Abstract
d-limonene is a plant extract with widespread application, and it has been recently reported to have antiproliferative and proapoptotic effects on cancer cells. However, the mechanisms by which d-limonene achieves these effects, especially in lung cancer, are not entirely clear. Therefore, the goal of this study was to examine the effects of d-limonene on lung cancer and explore its mechanisms of action.
DOI: 10.2147/OTT.S155716
PubMed: 29670359
Affiliations:
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Chine</country><wicri:regionArea>Hongqiao International Institute of Medicine, Shanghai Tongren Hospital & Faculty of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Qian, Ying" sort="Qian, Ying" uniqKey="Qian Y" first="Ying" last="Qian">Ying Qian</name><affiliation wicri:level="1"><nlm:affiliation>Hongqiao International Institute of Medicine, Shanghai Tongren Hospital & Faculty of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Hongqiao International Institute of Medicine, Shanghai Tongren Hospital & Faculty of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Deng, Xiaobei" sort="Deng, Xiaobei" uniqKey="Deng X" first="Xiaobei" last="Deng">Xiaobei Deng</name><affiliation wicri:level="1"><nlm:affiliation>Hongqiao International Institute of Medicine, Shanghai Tongren Hospital & Faculty of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Hongqiao International Institute of Medicine, Shanghai Tongren Hospital & Faculty of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Feng, Nannan" sort="Feng, Nannan" uniqKey="Feng N" first="Nannan" last="Feng">Nannan Feng</name><affiliation wicri:level="1"><nlm:affiliation>Hongqiao International Institute of Medicine, Shanghai Tongren Hospital & Faculty of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Hongqiao International Institute of Medicine, Shanghai Tongren Hospital & Faculty of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Yu, Herbert" sort="Yu, Herbert" uniqKey="Yu H" first="Herbert" last="Yu">Herbert Yu</name><affiliation wicri:level="2"><nlm:affiliation>Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI</wicri:regionArea><placeName><region type="state">Hawaï</region></placeName></affiliation></author><author><name sortKey="Qian, Biyun" sort="Qian, Biyun" uniqKey="Qian B" first="Biyun" last="Qian">Biyun Qian</name><affiliation wicri:level="1"><nlm:affiliation>Hongqiao International Institute of Medicine, Shanghai Tongren Hospital & Faculty of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Hongqiao International Institute of Medicine, Shanghai Tongren Hospital & Faculty of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author></analytic><series><title level="j">OncoTargets and therapy</title><idno type="ISSN">1178-6930</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">d-limonene is a plant extract with widespread application, and it has been recently reported to have antiproliferative and proapoptotic effects on cancer cells. However, the mechanisms by which d-limonene achieves these effects, especially in lung cancer, are not entirely clear. Therefore, the goal of this study was to examine the effects of d-limonene on lung cancer and explore its mechanisms of action.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li><li>États-Unis</li></country><region><li>Hawaï</li></region></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Yu, Xiao" sort="Yu, Xiao" uniqKey="Yu X" first="Xiao" last="Yu">Xiao Yu</name></noRegion><name sortKey="Deng, Xiaobei" sort="Deng, Xiaobei" uniqKey="Deng X" first="Xiaobei" last="Deng">Xiaobei Deng</name><name sortKey="Feng, Nannan" sort="Feng, Nannan" uniqKey="Feng N" first="Nannan" last="Feng">Nannan Feng</name><name sortKey="Lin, Hongyan" sort="Lin, Hongyan" uniqKey="Lin H" first="Hongyan" last="Lin">Hongyan Lin</name><name sortKey="Lv, Wenwen" sort="Lv, Wenwen" uniqKey="Lv W" first="Wenwen" last="Lv">Wenwen Lv</name><name sortKey="Qian, Biyun" sort="Qian, Biyun" uniqKey="Qian B" first="Biyun" last="Qian">Biyun Qian</name><name sortKey="Qian, Ying" sort="Qian, Ying" uniqKey="Qian Y" first="Ying" last="Qian">Ying Qian</name><name sortKey="Wang, Yu" sort="Wang, Yu" uniqKey="Wang Y" first="Yu" last="Wang">Yu Wang</name><name sortKey="Zhang, Shuo" sort="Zhang, Shuo" uniqKey="Zhang S" first="Shuo" last="Zhang">Shuo Zhang</name></country><country name="États-Unis"><region name="Hawaï"><name sortKey="Yu, Herbert" sort="Yu, Herbert" uniqKey="Yu H" first="Herbert" last="Yu">Herbert Yu</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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